Crystal Structure of Mycophenolic Acid. 6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methyl-hex-4-enoic Acid.
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چکیده
منابع مشابه
Crystal structures of 4-methoxy-6-methyl- and 4-hydroxy-6-methyl-2-pyrones.
interesting results because of the regular arrangement of the molecules in the environment.1–3 We previously reported on the photocycloaddition reaction of 4-methoxy-6-methyl-2-pyrone (1a) (Fig. 1) with maleimide (2) in the solid state to give a highly stereoselective [2 + 2] cycloadduct4 owing to the formation of two sets of 1:1 complex crystals between (1a) and (2) (Fig. 1).5 The crystal show...
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The title hydrate, C13H14N2O4·H2O, crystallizes with two formula units in the asymmetric unit (Z' = 2). The dihedral angles between the planes of the tetra-hydro-pyrimidine ring and the 4-hy-droxy-phenyl ring and ester group are 86.78 (4) and 6.81 (6)°, respectively, for one mol-ecule and 89.35 (4) and 3.02 (4)° for the other. In the crystal, the organic mol-ecules form a dimer, linked by a pai...
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The structure of the title compound, C(19)H(17)BrN(2)O(3), consists of two cyclic groups, viz. 4-(meth-oxy-carbon-yl)phenyl and 6-(4-bromo-phen-yl)-3-oxo-2,3,4,5-dihydro-pyridazin-4-yl, which are linked by a methyl-ene spacer. The pyridazine ring is twisted and the dihedral angle between its mean plane and that of the bromo-phenyl mean plane is 17.2 (2)°. The 4-(meth-oxy-carbon-yl)phenyl group ...
متن کاملCrystal structure of (6-bromo-2-oxo-2H-chromen-4-yl)methyl morpholine-4-carbodithioate
In the title compound, C15H14BrNO3S2, the 2H-chromene ring system is nearly planar, with a maximum deviation of 0.034 (2) Å, and the morpholine ring adopts a chair conformation. The dihedral angle between best plane through the 2H-chromene ring system and the morpholine ring is 86.32 (9)°. Intra-molecular C-H⋯S hydrogen bonds are observed. In the crystal, inversion-related C-H⋯S and C-H⋯O inter...
متن کامل4-(7-Acetoxy-6-methoxy-4-methyl-2-oxo-2H-chromen-3-yl)phenyl acetate
The title compound, C(21)H(18)O(7), is an important inter-mediate in the synthesis of 3-(4-hydroxy-phen-yl)-4-methyl-6-meth-oxy-7-hydroxy-coumarin, which is a nonsteroidal analogue of 2-methoxy-estradiol (2-ME). The substituent benzene ring is not in the same plane as the coumarin ring system, with a dihedral angle of 66.88 (10)°. There are some weak inter-molecular C-H⋯O inter-actions. One car...
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ژورنال
عنوان ژورنال: Analytical Sciences
سال: 2000
ISSN: 0910-6340,1348-2246
DOI: 10.2116/analsci.16.783